Here, the jet-set connoisseurs at Mr & Mrs Smith guide you to their favorite spots for sipping cocktails and shaking your tail feathers -- all without ever leaving your hotel. With swim-up pool bars and sky-high lounges, these international party pads are so happening, you might just forget to sleep.

Hidden behind a traditional 19th-century facade, the nightlife options at this futuristic boutique hotel are invigoratingly avant-garde. In addition to the main lounge -- a decadent split-level drinking den -- there's the Ice Kube, a bar where everything from the walls down to the tumblers are made out of ice. Reserve a half-hour vodka-sipping session; at the end your fingers might be numb, but you'll feel all warm and fuzzy inside.
Room to book: Each accommodation is tricked out with the latest gadgetry, but for the best views, ask for one of the terraced junior suites on a high floor.

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Originally built as a restaurant in 1863, this, the city's best-loved hotel and entertainment epicenter is the place to rock out to live bands. Grab a drink on the bustling terrace and then barhop your way through the other in-house watering holes -- the headliner bar is big enough to hold a double-decker bus -- before escaping back to your boudoir during the wee hours of the morning.
Room to book: Number 431's glamorous past -- it served as a dressing room for both Ella Fitzgerald and Marlene Dietrich -- makes it a must-stay. If size matters, the Clock Suite is the biggest, with panoramas out over the park.

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Living up to its reputation as the party hotel on South Beach, this hideaway draws Miami's glitterati like divas to diamonds. Its main nighttime attraction, Skybar, comprises four enticing areas: Kitted out with Moroccan furnishings and dim, sexy red lighting, Redroom's indoor lounge is an exotic affair. Lanterns light up the alfresco Redroom Garden, which has a Matisse-inspired, cobalt-blue palette. Rumbar, also outside, offers poolside posing aplenty and 75 different rums; the more diminutive beach-fronting Sandbar is reserved for exclusive shindigs.
Room to book: When it comes to checking in, the Beach House is where it's at with a private pool and outdoor dining and lounge area. Consider it one seriously indulgent slumber party.

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Luring the Riviera Maya's sun-seeking fiesta fiends, the pool-deck bar of this minimal, modern property serves up fantastic mixed drinks and bumping dance music. Stuff your suitcase with both bikinis and cocktail dresses: Days are idled away bronzing on king-size daybeds, but after dark, the hotel assumes a mantle of clubland sophistication.
Room to book: Accommodations are chic yet cheap, so you can afford to upgrade to one of the five balcony rooms, which come with hammocks for soaking up the rays. Know though, that this isn't the place for silent nights -- everything is clustered around the bar.

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This towering SoHo city slicker lures fashionistas, suits, and artists to its various hotspots. Before 9 p.m., use the hotel-guests-only policy at lively rooftop bar, Jimmy, to your advantage -- after that, you'll have to enter on the street with everybody else. The indoor Treehouse Bar gets the party started with 16 different flavors of margarita, including watermelon and yuzu. When the next day rolls around, take it easy with a movie in the Urban Garden during the hotel's regular film series.
Room to book: Honeymooners or die-hard romantics should snag the keys to the huge penthouse. Through wide windows on three walls, you can admire Manhattan in one skyline sweep.

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After years of being members-only, the Met Bar at this sophisticated escape has relaunched with a fresh face and an open-to-the-public policy. The decade-old veteran of the London scene even has a new beverage lineup, including chocolate-infused cocktails (that you'll order, and your husband will steal). The bar isn't the only place to see and be seen: the Met's Nobu outpost, serving modern Japanese cuisine, is packed nightly with movers and shakers.
Room to book: Live it up and go for the Penthouse Suite, which, with its floor-to-ceiling windows, features one of the most king-of-the-world views in the capital.

View more photos of the Metropolitan hotel.

The key to living it up at this urban getaway? Preparing with a long, delicious siesta. This is a late-night city, and the "in" crowd hangs out here 'til the early hours. Take your catnap by the rooftop swimming pool, overlooking the jumbled metropolis and the gorgeous Mediterranean sky. Start the night off with a drink at Omm's restaurant, Moo, before grabbing a table and sampling the Michelin-starred Catalan cuisine. (Reserve one of the low couches for a more private nook.) Then migrate to OmmSession, the hotel's scene-shaking club, which features live music and house-rocking DJs.
Room to book: Rooms looking out onto Paseo de Gracia avenue have the best vantage point; those facing the interior garden are blessed with bigger balconies.

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This hip three-story sanctuary possesses a trio of venues for sinking some drinks and tapping those toes. Settle onto one of the red-and-black curved couches at Bar Brick, with its soundtrack of lounge and jazz; pay a visit to the 24-hour honesty bar at the Green Terrace on the roof; or kick back on the distressed chesterfield sofa in the kitsch Lobby Bar. The after-dark fun doesn't stop there -- the boho Roma Norte district's buzzy bars are right at your doorstep.
Room to book: Reserve one of the two-level PH Lofts for their private terraces, which come with bathtubs and flat-screen TVs.

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With an impressive roster of lounges and eateries, this everything-under-one-roof destination will keep you busy until the sun comes up. The iconic Establishment Bar is set in a huge, white-columned room with a long, striking pale-marble bar and sleek modern sofas. Next door, the Gin Garden offers tasty concoctions, infused with lavender, orange, lime, and more. Upstairs, the hyper-colorful Hemmesphere is a glam cocktail space with low, Ottoman-inspired seating and exotic glass display cabinets.
Room to book: If you're feeling flashy, crash at the top-floor Loft Penthouse with a sleek living room, or the sprawling two-level Duplex Penthouse.

View more photos of the Establishment Hotel.

Live out your rock-star fantasies at this legendary L.A. party palace. Hedonistic and glamorous in equal parts, its history is as spectacular as its architecture. Saucy, saloonlike Bar Marmont mixes up a dream cocktail menu of perfectly poured, cleverly modernized classics: In addition to always-delicious fresh peach Bellinis, there are Plymouth gin Negronis and heady Ryka vodka, honey, and fig-puree medleys. Gastropub-style snacks, including cheese boards, heirloom-tomato salads, oxtail bruschetta, self-styled Damn Good Burgers, cater to every appetite.
Room to book: Hillside Bungalows offer the coolest midcentury decor, working fireplaces, private street entrances and carports, and direct access to the pool from a private walled garden.

View more photos of Chateau Marmont.

For more insider tips and to book your next trip, contact the travel experts at Mr and Mrs Smith (800-464-2040, mrandmrssmith.com).